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Pharmacological effect

The drug Xanax has anxiolytic, sedative, hypnotic, anticonvulsant, and central muscle relaxant effects on the body. The drug provides a moderately expressed hypnotic effect with the weakening of fear, anxiety, and a decrease in emotional stress. The drug helps improve sleep quality, reduces the period of falling asleep and the number of night awakenings, thereby increasing the duration of sleep.

The drug Xanax is used in the treatment of patients with:

• neurosis-like and neurotic disorders, accompanied by feelings of anger and anxiety;
• reactive depressive states against the background of the development of somatic diseases;
• panic disorders;
• insomnia, sleep disorders;
• withdrawal syndrome (including drug and alcohol withdrawal syndrome);
• irritability and tension;
• frequent decrease in mood;
• loss of appetite due to neuroses;
• development of phobias.

Instructions for use

Xanax is taken orally, regardless of the main meal.

The duration of treatment is determined strictly individually.

For depressive states and panic disorders, the drug is prescribed to adults in an initial dosage of 0.1-0.2 mg 2 or 3 times a day. After 1-2 weeks, the dosage is gradually increased if necessary.

Weakened or elderly patients are not recommended to prescribe the drug in a dosage exceeding 0.25 mg up to 3 times a day.

For sleep disorders, anxiety, and restlessness, the recommended dosage of the drug is 0.7-1.5 mg per day.

The maximum recommended daily dosage of the drug can be 10 mg.

The duration of treatment for acute conditions can reach 3-5 days.

If necessary, discontinuation of the drug is carried out gradually.

Contraindications

The use of Xanax is contraindicated for:

• the presence of individual hypersensitivity to the active and additional components of the drug;
• lactose intolerance;
• respiratory failure;
• severe dysfunction of the liver and kidneys;
• myasthenia gravis;
• acute attacks of glaucoma;
• in case of poisoning with psychotropic, sleeping pills, and narcotic drugs, as well as alcohol;
• chronic alcoholism;
• coma;
• shocked;
• pregnancy;

The drug Xanax is not used in pediatric practice.

Side effects

The following side effects may occur when taking Alprazolam:

• central nervous system – feeling of fatigue, drowsiness, decreased ability to concentrate, dizziness, disorientation, ataxia, slowed motor and mental reactions, gait instability, tremors, depression, euphoria, memory loss, depressed mood, impaired motor coordination, suicidal tendencies, fear, agitation, hallucinations, muscle spasms, anxiety, irritability, aggressive outbursts;
• digestive system - nausea, heartburn, drooling, dry mouth, liver dysfunction, vomiting, diarrhea, loss of appetite, jaundice, constipation;
• hematopoietic system – leukopenia, agranulocytosis (hyperthermia, chills, excessive weakness or fatigue), thrombocytopenia, anemia;
• urinary system - urinary retention, urinary incontinence, renal dysfunction, increased or decreased libido, dysmenorrhea;
• endocrine system - changes in body weight, menstrual irregularities;
• cardiovascular system – tachycardia, decreased blood pressure;
• allergic reactions - itching, skin rash.

Drug interactions of Xanax (Alprazolam) 

In persons with endogenous depression, the combined use of Xanax and antidepressants is allowed. When used simultaneously with sleeping pills, anticonvulsants, neuroleptic drugs, ethyl alcohol, narcotic analgesics, and muscle relaxants, a mutual enhancement of the effect is noted. The risk of adverse reactions increases when Alprazolam is used together with inhibitors of microsomal oxidation. A decrease in the effectiveness of the drug is observed when used simultaneously with inducers of microsomal oxidation. The anxiolytic increases the concentration of imipramine in the blood plasma.

It is important to follow your doctor's instructions and limits when using alprazolam. Take the drug strictly as prescribed, and do not exceed the indicated dosage. Be alert for any side effects and contact your doctor immediately if you experience problems or complications.

It is important to remember that obtaining a prescription for alprazolam is only one step in successfully treating anxiety disorders and panic attacks. Regular visits to your doctor, adherence to recommendations, and use of other treatments may be required to achieve long-term benefits.